Presence of Two Virus-Like Particles in Penicillium citrinum

Avian lymphoid leukosis: Virus-like particles in kidney Cells

Virus particles from conidia of Penicillium species.

Virus particles and their component double-stranded ribonucleic acid (dsRNA) have been isolated from conidia and mycelia of certain Penicillium species. The conidia and mycelia of P. stoloniferum NRRL 5267 contained 75 and 85 mug of dsRNA/g (dry weight), respectively. Of the total dsRNA released from NRRL 5267 conidia, 10% was nonencapsulated. Conidia of P. brevi-compactum NRRL 5260 and P. chry...

Double-stranded ribonucleic acid in viruses of Penicillium citrinum.

The nucleic acid content of two viral populations in a strain of Penicillium citrinum is shown to be double-stranded ribonucleic acid, resolved through polyacrylamide gel electrophoresis into 10 size groups ranging from 1.17 to 3.98 megadaltons.

Relationship between the biosynthesis of virus-like particles and mycophenolic acid in Penicillium stoloniferum and Penicillium brevi-compactum.

DETRO)", R, \\"., S. N. FREER, and D. I. FEC;C;ELL. 1973. Relationship betwcen the biosynthesis of viruslike panic!cs and mycophenolic acid in Pellicillilllll s!olonifertlli1 and Penicillium hrel'i-compaCfIlIll. Can. J. ivlicrobiol. 19: 1459-1462. Several strains of Penieillilllll s!olonZrerll'n and P. breci-compaCI/ll1l containing no virus-like particles (YLP) synthesize mycophenolic acid (MAl...

Lethality in mice of double-stranded ribonucleic acid from virus-like particles of Penicillium stoloniferum.

The LD 50 in mice of intact virus-like particles (VLP) from Penicillium stololllferum NRRL 5267 was greater than 240 mg/kg body weight, and their component double-stranded ribonucleic acid (dsRNA) was 34·0 mg/kg. Judged by decreases in LD50 values, administration of sublethal amounts of actinomycin D or cycloheximide simultaneously with sublethal amounts of intact VLP or mycoviral dsRNA enhance...